PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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In Vitro - in Vivo Extrapolation of Hepatic Clearance in

Utilizing virtual experiments to increase understanding of

Evidence of the need for modified well-stirred model in vitro to

PDF] Clearance Prediction Methodology Needs Fundamental

Precisely adjusting the hepatic clearance of highly extracted

Frontiers Use of physiological based pharmacokinetic modeling

Prediction of hepatic clearance in human from in vitro data for

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

Frontiers A Critical Perspective on 3D Liver Models for Drug

PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

Evidence of the need for modified well-stirred model in vitro to

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