Steady-State Principles
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Fig. 6.1 Achieving steady state with the use of: (A) a constant infusion (B) intermittent bolus dosing (C) an initial loading dose followed by intermittent doses A single bolus dose (loading dose) administered before the constant infusion or intermittent bolus doses (Fig. 6.1C) can accelerate the achievement of steady state. Here, the main factor determining the…
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