Example of a primary drying design space graph showing sublimation

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PDF) Recommended Best Practices for Lyophilization Validation—2021

Lyophilization: cycle robustness and process tolerances, transfer and scale up - European Pharmaceutical Review

Processes, Free Full-Text

Sublimation interface location versus primary drying time – a 8.25 mm

The left top panel represents minimum controllable pressure as a

Preservation of biomaterials and cells by freeze-drying: Change of paradigm - ScienceDirect

Pharmaceutics, Free Full-Text

PDF) Recommended Best Practices for Lyophilization Validation—2021

Akhilesh BHAMBHANI, Merck & Co., Whitehouse Station

Ehab MOUSSA, Senior Scientist, PhD, AbbVie, Illinois

Processes, Free Full-Text

Best Practices and Guidelines (2022) for Scale-up and Technology Transfer in Freeze Drying Based on Case Studies. Part 2: Past Practices, Current Best Practices, and Recommendations

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